【Name】Rimantadine Hydrochloride
C12H21N·HCl 215.77
This product is α-methyl tricyclo[3.3.1.13.7] decane-1-methylamine hydrochloride. Calculated as dry product, the content of C12H21N·HCl shall not be less than 99.0%.
[Properties] This product is white crystalline powder; odorless.
This product is easily soluble in methanol and soluble in water or ethanol.
[Content determination] Take 0.15g of this product, accurately weigh it, add 2ml of chloroform to dissolve, add 30ml of glacial acetic acid and 7ml of mercury acetate test solution, add 1 drop of crystal violet indicator solution, and use perchloric acid titration solution (0.1mol/ L) Titrate until the solution is blue, and correct the titration result with a blank test. Each 1ml of perchloric acid titrant (0.1mol/L) is equivalent to 21.58mg of C12H21N·HCl.
【Category】Antiviral drugs.
【Storage】Sealed and stored.
[Preparation] (1) Rimantadine hydrochloride tablets (2) Rimantadine hydrochloride granules